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澤間 善成 准教授  Associate Professor Yoshinari Sawama Ph.D.

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澤間善成准教授

澤間 善成 准教授

Associate Professor
Yoshinari Sawama Ph.D.

mail: sawama-at-gifu-pu.ac.jp

(-at-を@に変えてください)

略歴

2001.3     大阪大学薬学部 卒業

2003.3     大阪大学大学院薬学研究科 博士前期課程修了

2005.4-2006.3  日本学術振興会 特別研究員 (DC2)

2006.3       大阪大学大学院薬学研究科 博士後期課程修了

2006.4-2007.3  日本学術振興会 特別研究員 (PD)

2007.4     独国ドルトムント工科大学 博士研究員 (N. Krause 教授)

2009.5     立命館大学グローバル・イノベーション研究機構 博士研究員

2010.2- 2015.9 岐阜薬科大学 助教

2015.10-2017.6 岐阜薬科大学 講師

2017.7-     岐阜薬科大学 准教授

専門
有機合成化学、天然物合成、触媒有機化学
受賞

平成29年度 岐阜市職員表彰 有益な研究・発明

平成29年度(第30回)有機合成化学協会研究企画賞(三菱ケミカル研究企画賞)

2012年度 有機合成化学協会東海支部奨励賞

主な論文

(2017.7.3現在)

  1. Cyclic Ether Synthesis from Diols using Trimethyl Phosphate
    S. Asai, M. Kato, Y. Monguchi, H. Sajiki, Y. Sawama
    Chem. Commun. 53, 4787-4790 (2017).
  2. Phosphate-Mediated Enyne Synthesis from Allenols
    S. Asai, M. Kato, Y. Monguchi, H. Sajiki, Y. Sawama
    ChemistrySelect, 2, 876-878 (2017).
  3. Site-Selective Iron(III) Chloride-Catalyzed Arylation of 4-Aryl-4-methoxy-2,5-cyclohexadienones for the Synthesis of Polyarylated Phenols
    Y. Sawama, M. Masuda, R. Nakatani, H. Yokoyama, Y. Monguchi, T. Dohi, Y. Kita, H. Sajiki
    Adv. Synth. Catal. 358, 3683-3687 (2016).[selected as a Very Important Publication (VIP) and a cover picture]
  4. Additional Nucleophile-Free FeCl3-Catalyzed Green Deprotection of 2,4-Dimethoxyphenylmethyl-Protected Alcohols and Carboxylic Acids
    Y. Sawama, M. Masuda, A. Honda, H. Yokoyama, K. Park, N. Yasukawa, Y. Monguchi, H. Sajiki
    Chem. Pharm. Bull. 64, 778 (2016).
  5. Palladium on Carbon-Catalyzed Chemoselective Oxygen Oxidation of Aromatic Acetals
    N. Yasukawa, S. Asai, M. Kato, Y. Monguchi, H. Sajiki, Y. Sawama
    Org. Lett. 18, 5604-5607 (2016).
  6. Disiloxane Synthesis Based on Silicon-Hydrogen Bond Activation Using Gold and Platinum on Carbon in Water or Heavy Water
    Y. Sawama, M. Masuda, N. Yasukawa, R. Nakatani, S. Nishimura,  K. Shibata,  T. Yamada,  Y. Monguchi  H. Suzuka, Y. Takagi, H. Sajiki
    J. Org. Chem. 81, 4190-4195 (2016).
  7. Mild and Direct Multiple Deuterium-Labeling of Saturated Fatty Acids
    T. Yamada, K. Park, N. Yasukawa, K. Morita, Y. Monguchi, Y. Sawama, , H. Sajiki
    Adv. Synth. Catal. 358, 3277-3282(2016).
  8. Gold-Catalyzed Benzylic Azidation of Phthalans and Isochromans and Subsequent FeCl3-Catalyzed Nucleophilic Substitutions
    S. Asai, Y. Yabe, R. Goto, S. Nagata, Y. Monguchi, Y. Kita, H. Sajiki, Y. Sawama
    Chem. Pharm. Bull. 63, 757-761(2015).
  9. FeCl3-Catalyzed Self-Cleaving Deprotection of Methoxyphenylmethyl-Protected Alcohols
    Y. Sawama, M. Masuda S. Asai, R. Goto, S. Nagata, S. Nishimura, Y. Monguchi, H. Sajiki
    Org. Lett. 17, 434-437 (2015).
  10. Biaryl Synthesis by Ring-Opening Friedel–Crafts Arylation of 1,4-Epoxy-1,4-dihydronaphthalenes Catalyzed by Iron Trichloride
    Y. Sawama, S. Asai, T. Kawajiri, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 21, 2222-2229 (2015).
  11. Biarylmethane and Fused Heterocyclic Arene Synthesis via in Situ Generated o- and/or p-Naphthoquinone Methides
    Y. Sawama, T. Kawajiri, S. Asai, N. Yasukawa, Y. Shishido, Y. Monguchi, H. Sajiki
    J. Org. Chem. 80, 5556-5565 (2015).
  12. Stainless-Steel-Mediated Quantitative Hydrogen Generation from Water under Ball Milling Conditions
    Y. Sawama, M. Niikawa, Y. Yabe, R. Goto, T. Kawajiri, T. Marumoto, T. Takahashi, M. Itoh, Y. Kimura, Y. Sasai, Y. Yamauchi, S. Kondo, M. Kuzuya, Y. Monguchi, H. Sajiki
    ACS Sustainable Chem. Eng. 3, 683-689 (2015).
    [highlighted in Yomiuri Shimbun (15th, March, 2017) and Gifu Shimbun (22th, December, 2016)]
  13. Stainless-Steel Ball Milling Method for Hydro-/Deutero-genation using H2O/D2O as a Hydrogen/Deuterium Source
    Y. Sawama, T. Kawajiri, M. Niikawa, R. Goto, Y. Yabe, T. Takahashi, T. Marumoto, M. Itoh, Y. Kimura, Y. Monguchi, S. Kondo, H. Sajiki
    ChemSusChem, 8, 3773-3776 (2015).
  14. Palladium on Carbon-Catalyzed Aqueous Transformation of Primary Alcohols to Carboxylic Acids Based on Dehydrogenation under Mildly Reduced Pressure
    Y. Sawama, K. Morita, S. Asai, M. Kozawa, S. Tadokoro, J. Nakajima, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 357, 1206-1210 (2015).
    [highlighted in synfacts, 11, 0783 (2015); highlighted in Organic Chemistry Portal, March 14 (2016)]
  15. Hydrogen Self-Sufficient Arene Reduction to Cyclohexane Derivatives Using a Combination of Platinum on Carbon and 2-Propanol
    Y. Sawama, M. Mori, T. Yamada, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 357, 3667-3670 (2015).
    [selected as an inside cover picture]
  16. Multiple Deuteration of Alkanes Synergistically Catalyzed by Platinum and Rhodium on Carbon as a Mixed Catalytic System
    T. Yamada, Y. Sawama, K. Shibata, K. Morita, Y. Monguchi, H. Sajiki
    RSC Adv. 5, 13727-13732 (2015).
  17. Mild Deuteration Method of Terminal Alkynes in Heavy Water Using Reusable Basic Resin
    T. Yamada, K. Park, Y. Monguchi, Y. Sawama, H. Sajiki
    RSC Adv., 5, 92954-92957 (2015).
  18. Efficient Partial Hydrogenation of Trichloromethyl to gem-Dichloromethyl Groups in Platinum on Carbon-Catalyzed System
    Y. Sawama, T. Imanishi, R. Nakatani, Y. Fujiwara, Y. Monguchi, H. Sajiki
    Tetrahedron 70, 4540-4546 (2014).
    [highlighted in J. Synth. Org. Chem. ,Jpn, 73, 88 (2015)]
  19. Rhodium on Carbon-Catalyzed Hydrogen Scavenger- and Oxidant-free Dehydrogenation of Alcohols in Aqueous Media
    Y. Sawama, K. Morita,T. Yamada, S. Nagata, Y. Yabe, Y. Monguchi, H. Sajiki
    Green Chem. 16, 3439-3443 (2014).
    [highlighted in J. Synth. Org. Chem. ,Jpn, 72, 1175 (2014)]
  20. Iron-Catalyzed Friedel–Crafts Benzylation with Benzyl TMS Ethers at Room Temperature
    Y. Sawama, Y. Shishido, T. Kawajiri, R. Goto, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 20, 510-516 (2014).
  21. Chemoselective and Direct Functionalization of Methyl Benzyl Ethers and Unsymmetrical Dibenzyl Ethers by Using Iron Trichloride
    Y. Sawama, R. Goto, S. Nagata, Y. Shishido, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 20, 2631-2636 (2014).
  22. Efficient Generation of ortho-Naphthoquinone Methides from 1,4-Epoxy-1,4-dihydronaphthalenes and Their Annulation with Allyl Silanes
    Y. Sawama, Y. Shishido, T. Yanase, K. Kawamoto, R. Goto, Y. Monguchi, Y. Kita, H. Sajiki
    Angew. Chem. Int. Ed. 52, 1515-1519 (2013).
  23. Iron-Catalyzed Ring-Opening Azidation and Allylation of O-Heterocycles
    Y. Sawama, K. Shibata, Y. Sawama, M. Takubo, Y. Monguchi, N. Krause, H. Sajiki
    Org. Lett. 15, 5282-5285 (2013).
  24. Lewis Acid-Catalyzed Ring-Opening Functionalizations of 1,4-Epoxy-1,4-dihydronaphthalenes
    Y. Sawama, Y. Ogata, K. Kawamoto, H. Satake, K. Shibata, Y. Monguchi, H. Sajiki, Y. Kita
    Adv. Synth. Catal. 355, 517-528 (2013).
  25. Site-selective Deuterated-Alkene Synthesis Using Palladium on Boron Nitride
    Y. Yabe, Y. Sawama, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 19, 484-488 (2013).
  26. Platinum on Carbon-Catalyzed H-D Exchange Reaction of Aromatic Nuclei Due to Isopropanol-Mediated Self-Activation of Platinum Metal in deuterium oxide
    Y. Sawama, T. Yamada, Y. Yabe, K. Morita, K. Shibata, M. Shigetsura, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 355, 1529-1534 (2013).
  27. Easily-Controlled Chemoselective Hydrogenation by using Palladium on Boron Nitride
    Y. Yabe, Y. Sawama, T. Yamada, S. Nagata, Y. Monguchi, H. Sajiki
    ChemCatChem 5, 2360-2366 (2013).
  28. Platinum on Carbon-Catalyzed Hydrodefluorination of Fluoroarenes Using Isopropyl Alcohol-Water-Sodium Carbonate Combination
    Y. Sawama, Y. Yabe, M. Shigetsura, T. Yamada, S. Nagata, Y. Fujiwara, T. Maegawa, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 354, 777-782 (2012). [highlighted in synfacts, 8, 0802 (2012)]
  29. Stereo- and Regioselective Direct Multi-Deuterium-Labeling Methods of Sugars
    Y. Sawama, Y. Yabe, H. Iwata, Y. Fujiwara, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 18, 16436-16442 (2012).
  30. Development of palladium on boron nitride catalyst and its application to semihydrogenation of alkynes
    Y. Yabe, T. Yamada, S. Nagata, Y. Sawama, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 354, 1264-1268 (2012).
    [highlighted in synfacts, 8, 0001 (2012)]
  31. Platinum on carbon-catalyzed precise reduction control of trichloromethyl to geminal- dichloromethyl group
    T. Imanishi, Y. Fujiwara, Y. Sawama, Y. Monguchi, H. Sajiki
    Adv. Synth. Catal. 354, 771-776 (2012).
    [highlighted in synfacts, 8, 0684 (2012)]
  32. Iron-Catalyzed Chemoselective Azidation of Benzylic Silyl Ethers
    Y. Sawama, S. Nagata, Y. Yabe, K. Morita, Y. Monguchi, H. Sajiki
    Chem. Eur. J. 18, 16608-16611 (2012).
  33. Reversing the Reactivity of Carbonyl Functions with Phosphonium Salts: Enantioselective Total Synthesis of (+)-Centrolobine
    H. Fujioka, K. Yahata, O. Kubo, Y. Sawama, T. Hamada, T. Maegawa
    Angew. Chem. Int. Ed. 50, 12232-12235 (2011).
  34. An Unusual Reaction of a-Alkoxyphosphonium Salts with Grignard Reagents under an O2 Atmosphere
    H. Fujioka, A. Goto, K. Otake, O. Kubo, Y. Sawama, T. Maegawa
    Chem. Commun. 47, 9894-9896 (2011).
  35. Remarkable Effect of Phosphine on the Reactivity of O,P-acetal-Efficient Substitution Reaction of O,P-acetal
    H. Fujioka, A. Goto, K. Otake, O. Kubo, K. Yahata, Y. Sawama, T. Maegawa
    Chem. Commun. 46, 3976-3978 (2010).
  36. Regioselective Gold-Catalyzed Allylative Ring Opening of 1,4-Epoxy-1,4-dihydronaphthalenes
    Y. Sawama, K. Kawamoto, H. Satake, N. Krause, Y. Kita
    Synlett 14, 2151-2155 (2010).
  37. Highly Regioselective Gold-Catalyzed Ring-Opening Allylation and Azidation of Dihydrofurans
    Y. Sawama, Y. Sawama, N. Krause
    Org. Lett. 11, 5034-5037 (2009).
  38. First Total Synthesis of (R,R,R)- and (3R,5S,9R)-Bejarol by Gold-Catalyzed Allene Cycloisomerization and Determination of Absolute Configuration of the Natural Product
    Y. Sawama, Y. Sawama, N. Krause
    Org. Biomol. Chem. 6, 3573-3579 (2008).
  39. Reaction of the Acetals with TESOTf-Base Combination; Speculation of the Intermediates and Efficient Mixed Acetal Formation
    H. Fujioka, T. Okitsu, Y. Sawama, N. Murata, O. Kubo, R. Li, Y. Kita
    J. Am. Chem. Soc. 128, 5930-5938 (2006).
  40. Unexpected and Highly Chemoselective Deprotection of the Acetals from Aldehydes and not Ketones
    H. Fujioka, Y. Sawama, N. Murata, T. Okitsu, O. Kubo, S. Matsuda, Y. Kita
    J. Am. Chem. Soc. 126, 11800-11801 (2004).

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