最近の研究成果

最近の研究成果 Research Results 

13.Nishiyama K, Kobayashi T, Sato Y, Watanabe Y, Kikuchi R, Kanno R, Koshizuka T, Miyazaki N, Ishioka K, Suzutani T.
A Double-Blind Controlled Study to Evaluate the Effects of Yogurt Enriched with Lactococcus lactis 11/19-B1 and Bifidobacterium lactis on Serum Low-Density Lipoprotein Level and Antigen-Specific Interferon-γ Releasing AbilityNutrition. In Press.

12. Koshizuka T, Toriyabe K, Sato Y, Ikuta K, Ikeda T, Suzutani T.
Congenital cytomegalovirus infection via a re-infected mother with original antigenic sin: A case report.
Int J Infect Dis. 2018 Oct 16;77:87-89.

11.Koshizuka T, Sato Y, Kobiyama S, Oshima M, Suzutani T.
A two-step culture method utilizing secreted luciferase recombinant virus for the detection of anti-cytomegalovirus compounds. Micorbiol. Immunol. 2018 Oct;62(10):651-658. ,In Press.
doi: 10.1111/1348-0421.12645

10.Kobayashi R, Abe M, Oguri K, Torikai M, Nishimura T, Mori H, Koshizuka T, Inoue N.   Analysis of relationships between polymorphisms in the genes encoding the pentameric complex and neutralization of clinical cytomegalovirus isolates. Vaccine, in press. https://doi.org/10.1016/j.vaccine.2018.08.054

9.Takuya Miura, Reina Makino, Kouhei Yamada, Miku Matsuura, Misaki Okumura, Souichi Yamada, Shinji Watanabe, Naoki Inoue.  Differences in the effects of mutations in GP131, a guinea pig cytomegalovirus homologue of pentameric complex component UL130, on macrophage and epithelial cell infection.  J Gen Virol, in press.  doi:10.1099/jgv.0.001137

8.Xiaoxia Li, Wei Gong, Guanqing Wang, Zhenling Lu, Ningjun Wu, Chengxiang Lian, Ling Huang, Naoki Inoue. Titration of cell-associated varicella-zoster virus with the MV9G reporter cell line for antiviral studies. J Virol Methods 260:14-20, 2018. doi:10.1016/j.jviromet.2018.06.019

7.Naoki Inoue, Mao Abe, Ryo Kobayashi, Souichi Yamada. Vaccine development for cytomegalovirus. In: Kawaguchi Y., Mori Y., Kimura H. (eds) Human Herpesviruses. Adv Exp Med Biol. 1045:271-296, 2018. doi:10.1007/978-981-10-7230-7_13

6.Yamada K, Majima R, Yamaguchi T, Inoue N, Characterization of phenyl pyrimidine derivatives that inhibit cytomegalovirus immediate-early gene expression. Antivir Chem Chemother 26, 1-7 (2018).

5.Koshizuka T, Kobayashi T, Ishioka K, Suzutani T, Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases. Sci Rep 8, 4447 (2018).  doi: 10.1038/s41598-018-22682-2.

4.Yano A, Takahashi K, Mori Y, Watanabe S, Hanamura Y, Sugiyama T, Inoue N, Peyer’s patches as a portal for DNA delivery by Lactococcus lactis in vivo. Biol Pharm Bull, 41, 1-9 (2018).

3.Majima R, Shindo K, Yamaguchi T, Inoue N, Characterization of a thienylcarboxamide derivative that inhibits transactivation functions of cytomegalovirus IE2 and varicella zoster virus IE62, Antiviral Res., 140, 142-150 (2017).

2.Yasui R, Yamaguchi T, Inoue N, Identification and characterization of a novel anti-varicella zoster virus compound that targets the portal protein encoded by ORF54, Microbiol Immunol, 61, 398-402 (2017).

1.Fujii T, Oka A, Morioka I, Moriuchi H, Koyano S, Yamada H, Saito S, Sameshima H, Nagamatsu K, Tsuchida S, Inoue N, Newborn congenital cytomegalovirus screening based on clinical manifestations and evaluation of DNA-based assays for in vitro diagnostics, Ped Infec Dis J, 36, 942-946 (2017).